Publications

Publications

•  Cooper, D., Turinsky, A., Sensen, C., Hallgrimsson, B. (2006). Effect of Voxel Size on 3D Micro-CT Analysis of Cortical Bone Porosity. Calcified Tissue International 80(3):211-219
• Cooper, D.M.L., Thomas, C.D.L., Clement, J.G., Turinsky,A.L., Sensen, C.W.,  Hallgrímsson, B. (2007). Age-Dependent Change In The 3D Structure Of Cortical Porosity At The Human Femoral Midshaft. Bone. 40:957-965
• Meruvia-Pastor, O., Soh, J., Xiao, M., Schmidt, E., Logan, C., Boughner, J. C., Jones, N., Osborn, D., Santiago, J., Gittleman, J., Hallgrímsson, B., Sensen, C.W. Fast Interactive Integration of Cross-Sectional Image Datasets and Surface Data for Morphometric Analysis. Studies in Health Technology and Informatics. Medicine Meets Virtual Reality 17 - NextMed: Design for/the Well-Being (2009) 142:183-188
• Shu, X., Turinsky, A., Sensen, C.W., Maurer,F. A Case Study of the Implementation of Agile Methods in a Bioinformatics Project. (2007). Proceedings of the 8th International Conference on Agile Processes in Software Engineering and eXtreme Programming (XP 2007), (Springer), p169-170.
• Soh, J., Turinsky, A.L., Trinh, Q.M., Chang, J., Sabhaney, A., Dong, X., Gordon, P.M.K., Janzen, R.P.W., Hau, D., Xia, J., Wishart, D.S., Sensen, C.W. (2009) Spatiotemporal Integration of Molecular and Anatomical Data in Virtual Reality using Semantic Mapping. Int. J. Nanomedicine 4:79-89
• Turinsky, A.L., Fanea, E., Trinh, Q., Watt, S., Hallgrimsson, B., Dong, X., Shu, X., Stromer, J.N., Hill, J.W., Edwards, C., Groesnick, B., Yajima, M., Sensen, C.W. (2008). CaveMan: Standardized Anatomical Context for Biomedical Data Mapping. Anatomical Sciences Education 1(1):10-18.
• Turinsky, A.L., Fanea, E., Trinh, Q., Dong, X., Stromer, J.N., Shu, X., Wat, S.,  Hallgrímsson, B., Hill, J.W., Edwards, C., Grosenik, B., Yajima, M., Sensen, C.W. (2008) Integration of Genomic and Medical Data into a 3D Atlas of Human Anatomy. Studies in Health Technology and Informatics-MMVR 16:parallel, combinatorial, convergent, NextMed by Design. 132:526-531
• Turinsky, AL, Sensen, CW (2006) On the Way to Building an Integrated Computational Environment for the Study of Developmental Patterns and Genetic Diseases. International Journal of Nanomedicine 1(1):89-96
• Xiao, M., Soh, J., Meruvia-Pastor, O., Osborn, D., Lam, N., Hallgrímsson, B., Sensen C.W. (2009) An Efficient Virtual Dissection Tool to Create Generic Models for Anatomical Atlases. Studies in Health Technology and Informatics.  142:426-428.
• Xiao, M., Soh, J., Meruvia-Pastor, O., Schmidt, E., Hallgrimsson, B., Sensen. C.W. (2010). Building Generic Anatomical Models Using Virtual Model Cutting and Iterative Registration.  BMC Medical Imaging.  10(1): 5 E-Published ahead of Print Feb 8 2010.
  

Abstracts

• Sensen, C.W., Soh, J.,Turinsky, A.L., Fanea, E., Trinh, Q.,  Wat, S., Hallgrímsson, B., Dong, X., Shu, X.,  Hill, J.W., Edwards, C., Grosenik, B., Yajima, M. (2008) Touring into Human Anatomy for Virtual Head and Neck Surgery. Third International Conference of Advanced Digital Technology in Head and Neck Reconstruction, Cardiff, Wales, UK, p. 63.

Book Chapters

• Sensen, C.W., Soh, J. (2008) CAVEman, an Object-Oriented Model of the Human Body. In Sensen, C.W., Hallgrímsson, B. [Eds.] Advanced Imaging in Biology and Medicine - Technology, Software Environments, Applications. Springer Verlag, Heidelberg. pp. 289-300 
• Turinsky, A., Sensen, C.W. (2008) Virtual Reality Meets Functional Genomics. In S.A. Krawetz [ed.] Bioinformatics for Systems Biology. Humana Press, Totowa, NJ pp. 609-621

Presentations

• Meruvia-Pastor O., Soh J., Schmidt E., Boughner J.C., Xiao M., Jamnizcky H.A., Hallgrímsson B., Sensen C.W. (2009) Cell Distribution for Morphometrics Analysis Using Incremental Cell Search on Histology Samples of Mice Embryos. iCORE Summit, Banff AB, August  
• Sensen, C.W. From 2D to 4D Bioinformatics. CFIA (2007) Lethbridge, AB., Jan. 23 - 24
• Sensen, C.W. Three-Dimensional Presentation of Data. CFBS 49th Annual Meeting (2006) in Saskatoon, SK, June 13-18 
• Sensen, C.W. From 2D to 4D Bioinformatics. GfKl (2006) Berlin, Germany, March 8-10.
• Meruvia-Pastor, O., Soh, J., Xiao, M., Schmidt, E., Logan, C., Boughner, J.C., Jones, N., Osborn, D., Santiago, J., Gittleman, J., Hallgrímsson, B., Sensen, C.W. Fast Interactive Integration of Cross-Sectional Image Datasets and Surface Data for Morphometric Analysis. Medicine Meets Virtual Reality Education Conference (MMVR 17), January 2009, Long Beach, CA.
• Sensen C.W., Soh J.,Turinsky A.L., Fanea E., Trinh Q.,  Wat S., Hallgrímsson B., Dong X., Shu X.,  Hill J.W., Edwards C., Grosenik B., Yajima M. (2008) Touring into Human Anatomy for Virtual Head and Neck Surgery. Third International Conference of Advanced Digital Technology in Head and Neck Reconstruction, Cardiff, Wales, UK
• Turinsky, A.L., Fanea, E., Trinh, Q., Dong, X., Stromer, J.N., Shu, X.,  Wat, S.,  Hallgrimsson, B.,  Hill, J.W., Edwards, C.,  Grosenick, B., Yajima, M., Sensen, C.W.  Integration of Genomic and Medical Data into a 3D Atlas of Human Anatomy, Medicine Meets Virtual Reality 16,  Jan 2008, Long Beach, CA USA.
• Xiao M., Soh J., Meruvia-Pastor O., Schmidt E., Hallgrímsson B., Sensen C.W. (2009) Building Generic Anatomical Models Using Virtual Cutting and Iterative Registration. iCORE Summit, Banff AB, August
  
  
  

Posters

• Xiao, M., Soh, J., Meruvia-Pastor, O., Osborn, D., Lam, N., Hallgrímsson, B., Sensen C.W. (2009) An Efficient Virtual Dissection Tool to Create Generic Models for Anatomical Atlases. Medicine Meets Virtual Reality Educational Conference (MMVR 17), January 2009, Long Beach, CA
  
  

Developmental Genetics of Craniofacial Shape in Mice

• Bellido, G.G., Scanlon, M.G., Page, J.H., Hallgrímsson, B.  (2006). The bubble size distribution in wheat flour dough. Food Research International 39(10): 1058-1066
• Boughner, J.C., Buchtova, M., Fu, K., Diewert, V., Hallgrímsson, B., Richman, J.M. (2007). Embryonic development of Python sebae - I: Staging criteria and macroscopic skeletal morphogenesis of the head and limbs. Zoology 110(3): 212-230
• Boughner, J.C., Hallgrímsson, B.  (2008). Biological spacetime and the temporal integration of functional modules: a case study of dento-gnathic developmental timing.  Developmental Dynamics. 237(1):1:17
• Boughner, J.C., Wat, S., Diewert, V.M., Young, N.M., Browder, L.W., Hallgrimsson, B. (2008). Short faced mice and developmental interactions between the brain and the face.  Journal of Anatomy 213(6):646-662
• Cooper D. M., Thomas, C.D., Clement, J.G., Hallgrímsson, B. (2006) Three-dimensional microcomputed tomography imaging of basic multicellular unit-related resorption spaces in human cortical bone. Anat Rec A Discov Mol Cell Evol Biol 288A:806-16.
• Ford-Hutchinson, A.F., Ali, Z., Lines, S.E.,  Hallgrímsson, B., Boyd, S.K., Jirik, F.R. (2007). Inactivation of Pten in osteo-chondroprogenitor cells leads to epiphyseal growth plate abnormalities and skeletal overgrowth.  Journal of Bone and Mineral Research 22(8): 1245-1259
• Hallgrímsson, B., Brown, J.J.Y., Ford-Hutchinson, A., Sheets, D., Zelditch, M.L., and Jirik, F.R.  (2006). The Brachymorph Mouse and the Developmental-Genetic Basis for Canalization and Morphological Integration.  Evolution and Development.  8(1):61-73
• Hallgrímsson, B., Lieberman, D.E. (2008). Mouse Models and the Evolutionary Developmental Biology of the Skull. Integrative and Comparative Biology. 48(3):373-384.
• Hallgrímsson, B., Lieberman, D.E., Liu, W., Ford-Hutchinson, A., Jirik, F.R. (2007). Epigenetic Interactions and the Structure of Phenotypic Variation in the Cranium. Evolution and Development. 9(1):76-91
• Hendrikse, J.L, Parsons, T.E., Hallgrímsson, B..  (2007).  Evolvability as the Proper Focus of Evolutionary Developmental Biology.  Evolution and Development.  9(4):393-401.
• Jamniczky, H.A., Hallgrimsson, B. (2009).  Selection and the stability of covariance structure: a comparison of wild and laboratory muroid crania.  Evolution 63:1540-1556.
• Kristensen, E., Parsons, T.E., Hallgrimsson, B., Boyd, S.K. (2008).A novel 3D Image-based morphological method for phenotypic analysis.  IEEE Transactions on Biomedical Engineering  55(12):2826-2831
• Lazenby, R.A, Cooper, D.M.L, Angus, S., Hallgrímsson, B.  (2008) Articular Constraint, Handedness and Directional Asymmetry in the Human Second Metacarpal. Journal of Human Evolution, 54(6):875-885. ePub ahead of print Jan 11, 2008.
• Lieberman, D.E. , Hallgrimsson, B., Liu, W., Parsons, T.E.,Jamnizcky, H.A. (2008) Spatial Packing, Cranial Base Angulation and Craniofacial Shape Variation in the Mammalian Skull: testing a new model using mice.  Journal of Anatomy 212 (6):720-735.  
• Parsons, T.E., Hornung, L., Kristensen, E., Diewert, V., Boyd, S.K., German, R.Z, Hallgrímsson, B. (2008).  Phenotypic Variability and Craniofacial Dysmorphology: Increased Shape Variance in a Mouse model for Cleft Lip. Journal of Anatomy  212(2): 135-143
• Pontzer, H., Lieberman, D. E., Momin, E., Devlin, M. J., Polk, J.D., Hallgrímsson,B., Cooper, D.M.L.  (2006). Trabecular bone in the bird knee responds with high sensitivity to changes in load orientation. Journal of Experimental Biology. 209(1): 57-65. e-Published Dec 2005. 
• Rot-Nikcevic, I., Reddy, T., Downing, K.J., Belliveau, A.C.,Hallgrímsson, B., Hall, B.K., Kablar, B. (2006).  Myf5-/-:MyoD-/- amyogenic fetuses reveal the importance of early contraction and static loading by striated muscle in mouse skeletogenesis.  Development , Genes, and Evolution. 216 (1):1-9
• Willmore, K.E., Leamy, L, and Hallgrímsson, B. (2006). The Effects of Developmental and Functional Interactions on Mouse Cranial Variability through Late Ontogeny.  Evolution and Development. 8(6): 550-567.
• Willmore, K.E., Zelditch, M.I., Lozanoff, S., Young, N., Ah-Seng, A., Lozanoff, S., Hallgrímsson, B. (2006).  Canalization and Developmental Stability in the Brachyrrhine Mouse.  Journal of Anatomy.  208: 361-372.
• Young, N.M., Wat S., Diewert, V.M., Browder, L.W.,  Hallgrímsson, B. (2006). Comparative Morphometrics of Embryonic Facial Morphogenesis: Implications for Cleft Lip Etiology. Anatomical Record. 290(1):123-139
  

• Calof, A.L.,  Kawauchi, S., Hamilton, J., Santos, R., Lopez-Burks, M.E.,  Young, C.M., Hoang, M.P., Chua, A., Kitzes, L., Hallgrímsson, B., Lander, A.D. (2007). Developmental and neurological phenotypes of CdLS:  Insights from the Nipbl mutant mouse. Varenna, Italy 
• Hallgrímsson, B. The Structure of Variation and the Developmental Basis for Evolutionary Change.  J Morphol Dec 2007 268(12):1080.
• Hallgrímsson, B., Lieberman, D.E., Liu, W. (2007).  The Developmental Basis for Morphological Integration and the Structure of Variation in the Skull. American Association of Physical Anthropology, Philadelphia, April, 2007
• Lazenby, R. A, Cooper, D.M.L., Angus, S., Hallgrímsson, B.  (2007).  Trabecular, Articular and Cortical Asymmetry in the Human Second Metacarpal.  American Association of Physical Anthropology, Philadelphia, March, 2007
• Leiberman, D.E., Liu, W., Hallgrímsson, B. (2007).  The Epigenetic Funnel and the Cranial Base: how cranial base growth helps integrate interactions between the face and brain to constrain overall skull shape. American Association of Physical Anthropologists, Philadelphia, March, 2007
• McDougall, J.J., Andruski, B., Schuelert, N.,  Hallgrimsson, B., Matyas, J. (2008).  Objective Assessment of Joint Nociception Reveals A Disconnect Between Disease Severity And Pain Sensation In Osteoarthritis. Pain Res Manage. 13(2):143
• Parsons, T.E., Jones, N., Kristensen, E., Boyd, S.K., Hallgrímsson, B. (2007). High-throughput 3D Morphometrics and Phenotypic Analysis. Journal of Morphology 268(12):1115
• Parsons, T.E., Kristensens, E., Boyd, S.K., Hallgrímsson, B. (2006). A Novel High-Throughput 3d Morphometric Method for Mean Shape Visualization and Comparison.  Canadian Association of Physical Anthropology, Peterborough, on October, 2006
• Parsons, T.E., Kristensen, E., Boyd, S.K., Hallgrímsson, B. (2007). High Throughput Morphometrics and the Developmental Basis For Facial Length in Mice.  American Association of Physical Anthropologists, Philadelphia, March, 2007 
• Turnquist, J. E. , Cerroni, A.M, Faccia, K., Boyd, S.K., Hallgrimsson, B. (2007). Bone mineral density and trabecular structure in rhesus macaque (Macaca mulatta) lumbar vertebrae: a comparison of micro-CT and DEXA. American Society of Primatologists (ASP) - Winston-Salem, North Carolina, June 19 – 24.
• Wat, S., Boughner, J.C., Hallgrímsson, B. (2007). The developmental basis for adult craniofacial variation: a morphometric analysis of the “short-faced” Crf4 mouse mutant. J Morphol 268(12):1147
  

• Hall, B.K., Hallgrimsson, B. (2008). Strickberger's Evolution. Sudbury, MA: Jones and Bartlett Publishers
• Hallgrímsson, B. Anatomical Imaging and Post-Genomic Biology.  In  C. W. Sensen and B. Hallgrimsson, eds. Advanced Imaging in Biology and Medicine: Technology, Software Environments, Applications.  (2008). Springer Verlag
• Hallgrímsson, B., Boughner, J.C., Turinsky, A., Logan, C., Sensen, C.W. Geometric Morphometrics and the Study of Development.  In  C. W. Sensen and B. Hallgrimsson, eds. Advanced Imaging in Biology and Medicine: Technology, Software Environments, Applications.  (2008). Springer Verlag,
• Hallgrimsson, B, Lieberman, D.E., Young, N.E., Parsons, T.E., Wat, S. 2007. Evolution of Covariance in the Mammalian Skull. Novartis Found Symp 284:164-190 (Tinkering - The Microevolution of Development)
• Hallgrímsson, B., Zelditch, M.L, Parsons, T.E., Kristensen, E., Young, N.M., Boyd, S.K. Morphometrics and Biological Anthropology in the Post-Genomic Age. In: M.A. Katzenberg and S.R. Saunders, eds. Biological Anthropology of the Human Skeleton.  (2008). New York: John Wiley & Sons (Publication in January 2008)

Presentations

• Britton, J.E., Camacho, N.P. Hallgrímsson, B. (2006).  Effect of alendronate on craniofacial growth in the osteogenesis imperfecta murine model.  American Association of Orthodontists, Las Vegas, May 5-9
• Brown, J.J.Y., Marchuk, L.L., Shrive, N.G., Hallgrímsson, B., Frank, C.B. (2007). Site specific subchondral cancellous bone alteration in an ovine osteoarthritis model. Orthopaedic Research Society. San Diego, February 2007
• Calof, A.L., Kawauchi, S., Hamilton, J., Santos, R., Lopez-Burks, M.E.,  Young, C.M., Hoang, M.P., Chua, A., Kitzes, L., Hallgrímsson, B. Lander, A.D.. (2007). Developmental and neurological phenotypes of CdLS:  Insights from the Nipbl mutant mouse. Varenna, Italy
• Ford-Hutchinson, A.F., Ali, Z., Lines, S.E., Hallgrímsson, B., Boyd, S.K.,  Jirik, F.R. (2006) Skeletal overgrowth in mice lacking chondrocyte expression of the Pten tumor suppressor. American Society for Bone and Mineral Research, Philadelphia, Sept. 15-19, 2006
• Hallgrimsson, B.  Darwin's Fundamental Insight: The Study of Variation in Evolution, Development, and Medicine.   Darwin Bicentennial Lecture.  School of Medicine, University of Puerto Rico.  San Juan, Puerto Rico, U.S.A.  Sept 15 2009 
• Hallgrimsson, B. De Beer Was Right! A Middle-Out Approach to Understanding Craniofacial Variation.  Oral and Craniofacial Biology Speaker Series.  University of California, San Francisco.  San Francisco, CA, Aug 4 2009
• Hallgrímsson, B. “Evolution of Covariance”. (2006). Novartis Foundation Symposium. Tinkering: The Microevolution of Development, July 11 – 13, 2006.
• Hallgrímsson, B. How does Development Structure Phenotypic Variation in the Mammalian Skull?  Ecology and Evolution Seminar.  Dept. of Biological Sciences, University of Calgary, Calgary, AB. Sept. 20, 2006
• Hallgrímsson, B. “Morphometrics and Post-Genomic Evolutionary and Developmental Biology”. (2006). University of Vienna, Department of Anthropology, Morphofest Symposium in Vienna, Austria - July 18, 2006.
• Hallgrimsson, B.  Taking the Middle Road: A Model Organism-Based Approach to Human Evolutionary Developmental Biology.  Human Evolutionary Developmental Biology Workshop.  Konrad Lorenz Institute. Altenburg, Vienna, Austria.  Sept 3 - 6, 2009 
• Hallgrimsson, B. (2009).  The Developmental Basis for Phenotypic Variation. Interdiscplinary Symposium on Evolutionary Novelty.  University of Alberta, Edmonton, AB, Nov. 15.
• Hallgrimsson, B. (2009). The Middle-Out Approach to Development and the Evolutionary Developmental Biology of the Mammalian Skull. Evolutionary Morphology Seminar, The University of Chicago, Chicago, IL, USA. Nov. 30
• Hallgrimsson, B. (2009). The Phenogenomics of Craniofacial Shape. Dept. of Medical Genetics Seminar. The University of Colorado, Denver, CO, USA Oct. 8
• Hallgrímsson, B. The Structure of Phenotypic Variation: An Emerging Agenda for Evolutionary Developmental Biology.  Dept. of Psychology.  University of Lethbridge. Lethbridge, Alberta, April 11, 2007
• Hallgrímsson, B. (2007). The Structure of Variation and the Developmental Basis for Evolutionary Change.  International Congress of Vertebrate Morphology, Paris, France, July.
• Hallgrímsson, B. (With Lieberman, D.).  The Epigenetic Basis for Evolutionary Change in the Mammalian Skull.  Craniofacial Biology Gordon Research Conference, Ventura, CA, Jan 22., 2006
• Hallgrímsson, B., Leiberman, D.E., Ford-Hutchinson, A.F., Jirik, F.R. (2006). “Relative Growth of the Chondrocranium as a Determinant of the Shape of the Mammalian Skull”. Canadian Society of Zoologists in Edmonton, AB - May 2 – 6, 2006.
• Hallgrímsson, B., Lieberman, D.E., Liu, W. (2007).  The Developmental Basis for Morphological Integration and the Structure of Variation in the Skull. American Association of Physical Anthropologists, Philadelphia, April, 2007
• Kristensen, E., Parsons, T.E., Hallgrimsson, B., Boyd, S. (2006). A high-throughput method to quantify shape differences for micro-computed tomography.  World Conference of Biomechanics, Munich, Germany, July 29-Aug. 4.
• Kristensen, E., Parsons, T.E., Hallgrimsson, B., Boyd, S. (2006). A Novel Method of Mean Shape Comparison for Developmental Morphology and Bone Disease Research Using Micro-Computed Tomography.  American Society for Bone and Mineral Research, Philadephia, Sept. 15-19
• Lander, A.D., Kawauchi, S., Santos, R., Lopez-Burks, M.E., Hoffman, T., Young, C.M., Hoang, M.P., Chua, A., Lao, T., Lechner, M.S., Hallgrímsson, B., Schilling, T.F., Calof, A.L. (2007). Vertebrate animal models of Nipbl deficiency.  Varenna, Italy
• Lazenby, R.A.,  Cooper, D.M.L., Angus, S., Hallgrímsson, B. (2006) A Tale of Heads: 3D Trabecular Microarchitecture in Paired Second Metacarpals as a Test of the Articular Constraint Model.  Canadian Association of Physical Anthropology, Peterborough, on October, 2006
• Lazenby, R. A, Cooper, D.M.L., Angus, S., Hallgrímsson, B.  (2007).  Trabecular, Articular and Cortical Asymmetry in the Human Second Metacarpal.  American Association of Physical Anthropologists, Philadelphia, March, 2007
• Lazenby, R., Cooper, D.M.L., Hallgrímsson, B.  (2007). A microCT study of site specific variation in trabecular microarchitecture within the human second metacarpal.  International Bone and Mineral Society, June 24-29 Montreal, Canada.
• Leiberman, D.E., Liu, W., Hallgrímsson, B. (2007).  The Epigenetic Funnel and the Cranial Base: how cranial base growth helps integrate interactions between the face and brain to constrain overall skull shape. American Association of Physical Anthropologists, Philadelphia, March, 2007
• Parsons, T.E., Jones, N.,  Kristensen, E., Boyd, S.K., Hallgrímsson, B. (2007). High-throughput 3D Morphometrics and Phenotypic Analysis. International Congress of Vertebrate Morphology, Paris, France, July 2007
• Parsons, T.E., Kristensens, E., Boyd, S.K., Hallgrímsson, B. (2006). A Novel High-Throughput 3d Morphometric Method for Mean Shape Visualization and Comparison.  Canadian Association of Physical Anthropology, Peterborough, on October, 2006
• Parsons, T.E., Kristensen, E., Boyd, S.K.,  Hallgrímsson, B. (2007). High Throughput Morphometrics and the Developmental Basis For Facial Length in Mice.  American Association of Physical Anthropologists Annual Meeting, Philadelphia, March, 2007
• Parsons, T.E., Wat, S.,  Diewert, V.M., German, R.Z., Hallgrímsson, B. (2006). Ontogenetic development of craniofacial variablity in A/WySnJ mouse. Canadian Society of Zoologists.  Edmonton, Alberta, May 2-6, 2006
• Schmidt E.J., Parsons T.E., Jamniczky H.A., Gitelman J., Trpkov C., Boughner J., Logan C.C., Sensen C.W., Hallgrímsson B. (2010) Micro-computed tomography-based phenotypic approaches in embryology: Sources and effects of procedural artifacts on assessments of embryonic craniofacial growth and development. BMC Developmental Biology (in press)
• Turnquist, J. E., Cerroni, A.M., Faccia, K., Boyd, S.K., Hallgrimsson, B. (2007). Bone mineral density and trabecular structure in rhesus macaque (Macaca mulatta) lumbar vertebrae: a comparison of micro-CT and DEXA. American Society of Primatologists (ASP) - Winston-Salem, North Carolina, June 19 – 24.
• Wat, S., Boughner, J.C., Hallgrímsson, B. (2007). The developmental basis for adult craniofacial variation: a morphometric analysis of the “short-faced” Crf4 mouse mutant.  International Congress of Vertebrate Morphology, Paris, France, July 2007
• Wat, S., Young, N., Browder, L., Diewert, V., Hallgrímsson, B. (2006) The Crf4 mutation and the developmental basis for variation in facial length. Canadian Society of Zoologists.  Edmonton, Alberta, May 2-6, 2006
• Willmore, K.E., Hallgrímsson, B. (2006).  The effects of developmental and functional interactions on mouse cranial variability at different ages.  American Association for Physical Anthropologists Annual Conference.  Anchorage, Alaska, March, 2006
• Young, N.M., Wat, S., Diewert, V., Hallgrímsson, B. (2006). “The relationship of embryonic facial process size to facial length”. Society for Integrative and Comparative Biology Orlando, FLA - January 2006.

Posters

• McDougall, J.J., Andruski, B., Schuelert, N., Hallgrimsson, B., Matyas, J. (2008).  Objective Assessment of Joint Nociception Reveals A Disconnect Between Disease Severity And Pain Sensation In Osteoarthritis. Canadian Pain Society Annual Meeting, Victoria BC.

• Alirezaei, M, Fox, HS, Flynn, CT, Moore, CS, Hebb, AL, Frausto, RF, Bhan, V, Kiosses, WB, Whitton, JL, Robertson, GS, Crocker, SJ. Elevated ATG5 expression in autoimmune demyelination and multiple sclerosis. Autophagy. 2009;5(2): 152-158
• Hebb, A.L.O., Moore, C.S., Bhan, V., Campbell, T., Fisk, J.D., Robertson, H.A., Thorne, M., Lacasse, E., Holcik, M., Gillard, J., Crocker, S.J.,  Robertson, G.S. Expression of the Inhibitor of Apoptosis Protein Family in Multiple Sclerosis Reveals a Potential Immunomodulatory Role during Autoimmune Mediated Demyelination. Mult Scler. 2008 Jun;14(5):577-94.
• Hebb, AL, Moore, CS, Bhan, V, Robertson, GS. Targeting apoptosis to treat multiple sclerosis. Curr Drug Discov Technol. 2008;5(1):75-7.
• Moore, C.S., Earl, N., Frenette, R., Styhler, A., Mancini, J.A., Nicholson, D.W., Hebb, A.L., Owens, T., Robertson, G.S. (2006). “Peripheral Phosphodiesterase 4 Inhibition Produced by 4-[2-(3,4-Bis-difluoromethoxyphenyl)-2-[4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)-phenyl]-ethyl] methylpyridine -1-oxide (L-826, 141) Prevents Experimental Autoimmune Encephalomyelitis”. J Pharmacol Exp Ther. 2006. 319(1):63-72
• Moore, C.S., Hebb ALO, Robertson G.S.. Inhibitor of apoptosis protein (IAP) profiling in experimental autoimmune encephalomyelitis (EAE) implicates increased XIAP in T lymphocytes. Journal of Neuroimmunology (2008).193(1-2):94-105. Epub 2007 Dec 4.
• Moore, C.S., Hebb, A.L.O., Blanchard, M.M., Crocker, C.E., Liston, P., Korneluk, R.G., Robertson, G.S. Increased X-linked inhibitor of apoptosis protein (XIAP) expression exacerbates experimental autoimmune encephalomyelitis (EAE). J Neuroimmunol. (2008) 203(1):79-93
• Thorne, M., Moore, C.S., Robertson, G.S. Lack of TIMP-1 increases severity of experimental autoimmune encephalomyelitis: Effects of darbepoetin alfa on TIMP-1 null and wild-type mice. J Neuroimmunol. (2009) 211(1-2):92-100.
• Wang, J., Menchenton, T., Yin, S., Yu, Z., Bance, M., Morris, D.P., Moore, C.S., Korneluk, R.G., Robertson, G.S. Over-expression of X-linked inhibitor of apoptosis protein slows presbycusis in C57BL/6J mice. Neurobiol Aging. 2008 Aug 26. [Epub ahead of print]
• Zehntner, S.P., Bourbonnière, L., Moore, C.S., Morris, S.J., Methot, D., St Jean, M., Lacasse, E., Hebb, A.L., Robertson, G.S., Durkin, J., Gillard, J.W., Owens, T. (2007)  X-linked Inhibitor of Apoptosis (XIAP) Regulates T Cell Effector Function. Journal of Immunology. 179(11):7553-60.

• Hebb, A.L.O., Bhan, V., Moore, C.S., Soundararajan, R., Robertson, H.A., Gillard, J.,  Robertson, G.S. (2006). Patterns of immune cell expression of members of the Inhibitors of Apoptosis family distinguish between subtypes of Multiple Sclerosis. Multiple Sclerosis (2007) 13:280-307.
• Moore, C.S., Blanchard, M., Hebb, A.L.O., Belland, E.R., Anger, G.J., Liston, P., Robertson, G.S. (2005). Overexpression of XIAP in immune cells increases the severity of experimental autoimmune encephalomyelitis in C57BL/6 mice. Society for Neuroscience Annual Meeting Abstracts. (Presentation 902.13) (Washington DC, USA) 

• Hebb, A.L.O, Moore, C.S., Campbell, T., Bhan, V., Robertson, G.S. XIAP Associated Factor-1:  Putative Marker for IFN-B Responsiveness in Multiple Sclerosis. Neuroinflammation conference, Montreal Quebec, May 2009
• Moore, C.S., Hebb, A.L.O., Robertson, G.S. (2007). Co-administration of AEG35169 and Interferon-B produce a synergistic reduction of clinical serverity in experimental autoimmune encephalangelitis. ACTRIMS, Washington D.C., USA June 5.
• Moore, C.S.,  Hebb, A.L.O., Robertson, G.S. (2007), Profiling inhibitors of apoptosis (IAP) proteins in experimental autoimmune encephalomyelitis (EAE) implicates X-linked inhibitor of apoptosis (XIAP) in peripheral and encephalitogenic T cells end MS Meeting, Banff, AB, Dec. 2007
• Moore, C.S. Hebb, A.L.O., Robertson, G.S. Targeting XIAP as a novel therapeutic approach for decreasing severity of EAE The Canadian Society of Transplantation
• Moore, C.S., Hebb, A.L.O., Bhan, V., Fisk, J., Robertson, H.A., Murray, T.J., Korneluk, R. G., Gillard, J., Robertson, G.S. (2006). X-Chromosome-linked inhibitor of apoptosis (XIAP) and XIAP associated factor-1 (XAF-1): Markers of Disease Severity and Interferon-beta responsiveness. American Academy of Neurlogy. San Diego, CA.
• Robertson, G.S., Blanchard, M.M., Crocker, C., Korneluk, R.G., Hebb, A.L.O, Moore, C.S. Increased X-linked inhibitor of apoptosis protein (XIAP) expression exacerbates experimental autoimmune encephalomyelitis (EAE), Society for Neuroscience,  Monday, Nov 17, 2008, 8:00 AM - 9:00 AM  Washington Convention Center, Poster#: 350.13/Y4.

Presentations

• Hebb, A.L.O., Bhan, V., Moore, C.S., Soundararajan, R., Robertson, H.A., Gillard, J. Robertson, G.S. (2006). Patterns of immune cell expression of members of the Inhibitors of Apoptosis family distinguish between subtypes of Multiple Sclerosis.   Americas Committee on the Treatment of Multiple Sclerosis (ACTRIMS) Chicago, IL, October 8
• Hebb, A.L.O, Robertson, G.S., Diagnostic Markers in Multiple Sclerosis: Focus on the IAPs (Max-Planck Institute in Munster, Germany), April 27, 2006
• Hebb A.L.O, Robertson, G.S.,( 2007) Inhibitor of apoptosis protein expression in MS:  Possible regulatory function in autoimmune mediated demyelination. endMS meeting , Banff, AB Dec 
• Robertson, G.S.  Apoptotic genes as diagnostic markers in MS. University of British Columbia Sept 2007
• Robertson, G.S., Blanchard, M.M., Crocker, C., Korneluk, R.G., Hebb, A.L.O., Moore, C.S. Increased X-linked inhibitor of apoptosis protein (XIAP) expression exacerbates experimental autoimmune encephalomyelitis (EAE), Society for Neuroscience,  Monday, Nov 17, 2008, Washington, DC, USA.
   

Publications

• Fueger, P.T., Li, C.Y., Ayala, J.E., Shearer, J., Bracy, D.P., Charron, M.J., Rottman, R.N., Wasserman, D.H. Glucose Kinetics and Exercise Tolerance in GLUT4 Null C57BL/6 Mice. (2009). Journal of Physiology. 582(Pt 2):801-12.
• Fueger P.T., Lee-Young, R.S., Shearer J., Bracy, D.P., Heikkinen, S., Laakso, M., Rottman, J.N., Wasserman D.H. Phosphorylation Barriers to Skeletal and Cardiac Muscle Glucose Uptakes in High Fat Fed Mice: Studies in Mice with a 50% Reduction of Hexokinase II. (2007) Diabetes. 56(10):2476-84, 
• Fueger P.T., Lee-Young, R.S., Shearer J., Bracy, D.P., Heikkinen, S., Laakso, M., Rottman, J.N., Wasserman D.H. Phosphorylation Barrier to Muscle Glucose Uptake in High Fat Fed Mice: Studies in Mice with a 50% Reduction of Hexokinase II. Diabetes. (2007);56(10):2476-84
• Hittel, D.S., Berggren, J.R., Shearer, J., Boyle, K, Houmard, J.A. Increased Secretion and Expression of Myostatin in Skeletal Muscle from Extremely Obese Women. (2009)  Diabetes 58(1): 30-38. Epub Oct 3 2008.
• Shearer, J. Coenen, K.R., Pencek, R.R., Swift, L. L., Wasserman, D.H., Rottman, J.N. Long Chain Fatty Acid Uptake In Vivo: Comparison of [125I]-BMIPP and [3H]-Bromopalmitate.  Lipids. (2008) 43(8):703-11,  E-Published May 15 2008.
• Shearer, J., Duggan, G., Hittel, D.S., Wasserman, D.H., Vogel, H.J. Metabolomic Profiling of Dietary-Induced Insulin Resistance in The High Fat Fed C57BL/6J Mouse. Diabetes, Obesity and Metabolism. (2008) 10(10):950-958 ePublished Jan 22 2008
• Shearer, J., Fueger, P.T., Wang, Z., Bracy, D. P., Wasserman, D.H., Rottman, J.N. Metabolic Implications of Reduced Heart-Type Fatty-Acid Binding Protein in Insulin-Resistant Cardiac Muscle. BBA - Molecular Basis of Disease. (2008) 1782(10):586-92
• Shearer, J., Severson, D. L., Su, L., Belardinelli, L., Dhalla, A. K. Partial A1 Adenosine Receptor Agonist Regulates Cardiac Substrate Utilization in Insulin Resistant Rats In Vivo. Journal of Pharmacology & Experimental Therapeutics. (2009) 328(1):306-11, 2009
  

Abstracts 

• Brusselers, O., Severson, D., Hittel, D.S., Su, L., Sensen, C., Shearer, J. Dietary Induced Insulin Resistance Leads to Altered Substrate Availability and Early Cardiac Remodeling in the C57BL6J Mouse - NAASO Meeting 2008, Oct. 3 - 7, Phoenix
• Chan, C.Y.W., Ross, K.D., Carley, A.N., ., Carroll, R., Severson, D.L., Shearer, J.  Insulin-Resistance Induced Elevations in Cardiac Glycogen are not Attenuated by Regular Exercise. FASEB Meeting 2006.
• Duggan, G., Hittel, D.S., Lee, R.K., Tunnicliffe, J.M., Vogel, H.J., Shearer, J.  Contribution of Diet to Abnormal Metabolomic Profile in Dietary-Induced Insulin Resistance. Obesity Network, National Obesity Summit. Presentation #2122, Kananaskis, AB, May 7 - 11, 2009
• Duggan, G., Hittel, D.S., Tunnicliffe, J.M., Weljie, A., Vogel, H.J., Shearer, J.  Metabolomic Profiliing of Exercise-Induced Weight Loss in a model of Dietary Obesity. Keystone Symposia, Obesity: Novel Aspects of the Regulation of Body Weight (J4 - #327), Banff, AB. Jan 20-25, 2009.
• Duggan G.E., Vogel H.J., Shearer J., Weljie A.M. NMR Spectral Alignment for Multivariate Analysis of Type I and Type II Diabetic Mouse Models. Metabolomics Society Meeting, 2006.
• Duggan, G.E., Weljie, A., Vogel, H., Shearer, J. Prediction of Dietary-Induced Insulin Resistance in Mice by Targeted Profiling of Magnetic Resonance Spectra. CFBS Meeting 2007.
• Eller, L., Shearer, J., Reimer, R.A. Leucine not calcium improves insulin sensitivity in obese rats.  Keystone Symposia, Obesity: Novel Aspects of the Regulation of Body Weight (J4 - #154), Banff, AB. Jan 20-25, 2009.
• Fueger, P.T., Ayala, J.E., Shearer, J., Bracy, D.P., Charron, M.J., Rottman, J.N., Wasserman D.H. Basal and exercise-stimulated cardiac glucose uptake is preserved in GLUT4 null mice.  American Diabetes Association Meeting 2006.
• Fueger, P.T., Lee-Young, R.S., Shearer, J., Bracy, D.P., Heikkinen, S., Markku, L., Wasserman, D.H. Interaction of high fat feeding and impaired glucose phosphorylation capacity in control of muscle glucose uptake during insulin stimulation and exercise.  American Diabetes Association Meeting 2007.
• Hittel, D.S., Berggren, J.R., Shearer, J., Boyle, K ,  Houmard, J.A.. The Expression and Secretion of Myostatin from Skeletal Muscle is Increased in Extremely Obese and Insulin Resistant Women.  CSEP Annual Meeting, 2008., Oct. 15 - 18th, Banff, AB. 
• Hughey, C.C., Ma, L., James, F.D., Young, P.P., Wasserman, D.H., Rottman, J.N., Shearer, J. (2009).  Stem Cell Therapy Reduces Futile Respiration and Increases Electron Transport Chain Efficiency following Myocardial Infarction. Libin Research Day, University of Calgary, November.   
• Hughey, C. H., Zadeh, Z.E., Mazursky, S., MacIntosh, B., Shearer, J. Fiber Type-Specific Alterations in Skeletal Muscle Mitochondrial Oxidiative Phosphorylation following Induction of Heart Failure. NIH - Mitochondrial Biology in Cardiovascular Health & Diseases Meeting. Bethesda, Maryland.  Oct 6-7, 2008.
• Hughey, C.C., Wilson, R.J., Lee, R.K., Hittel, D.S., Severson, D.L., Shearer, J. Characterization of elevated glycogen in cardiac dysfunction induced by high fat feeding in the C57BL/J mouse. CSEP Annual Meeting, 2008. , Oct. 15 - 18, Banff, AB. 
• Hughey, J., Saint-Jean, L., Young, P.P., Shearer, J. (2009). Mitochondrial Characteristics Influencing Enhanced Multipotent Mesenchymal Stem Cell Engraftment in the Ischemic Heart.  Libin Research Day, University of Calgary, November.  
• Ross, K.D., Shearer, J., Carley, A.N., Chan, C.Y.W., Carroll, R., Severson, D.L. Exercise-Induced Increase in Pro-and Macroglycogen Content in Hearts from Type 1 Diabetic Mice.  FASEB Meeting 2006.
• Shearer, J., Binas, B., Wasserman, D.H., Wang, Z., Rottman, J.N. Cardiovascular consequences of heart-type fatty acid binding protein (FABP3) deletion in conscious C57BL/6 mice.  American Diabetes Association Meeting 2006
• Sarna, N., Brusselers, O., Shearer, J., Hittel, D. (2009). The Convergence Myostatin Signaling and Insulin Sensitivity in the C57BL/6J Mouse. 27th Annual Scientific Meeting of the Obesity Society.  126-OR. 17:S2, S83. November.
• Sarna, N., Hughey, C., Shearer, J., Hittel, D.S. (2009). A High-fat Diet Leads to Increases in Mitochondrial Content but Lowered Respiration Rates: An Apparent Paradox? 27th Annual Scientific Meeting of the Obesity Society. 128-OR 17:S2, S83, November.
• Shearer, J., Severson, D., Su, L., Belardinelli, L., Dhalla, A. Partial A1 Adenosine Receptor Agonist Regulates Cardiac Substrate Utilization In Vivo - NAASO Meeting, 2008, Oct. 3 - 7, Phoenix
• Shearer, J., Terchinsky, J., Wright, D. Decreased mitochondrial enzyme content in adipose tissue following the consumption of a high fat diet is associated with oxidative stress.  FASEB Meeting 2007.

Presentations

• Shearer, J. Dietary-Induced Insulin Resistance: Role of Exercise. Department of Kinesiology. University of Calgary. Calgary, AB. Sept 2006.
• Shearer, J. Metabolic Inflexibility in Obesity and Insulin Resistance. Canadian Obesity Network, Professional Seminar Presentations. University of Calgary. Calgary, AB. Sept 2007
  

Posters

• Shearer, J., Severson, D., Su, L., Belardinelli, L., Dhalla, A. Partial A1 Adenosine Receptor Agonist Regulates Cardiac Substrate Utilization In Vivo - NAASO Meeting, 2008, Oct. 3-7, Phoenix
• Zadeh, Z.E., Hittel, D., Severson, D., Heppie, R., Sensen, C., Shearer, J. High Fat Feeding Increases Mitochondrial Content while Compromising Outer Membrane Integrity - NAASO Meeting, 2008, Oct. 3-7, Phoenix.

  Publications

• Cheng, D., Knox, C., Young, N., Stothard, P., Damaraju, S., Wishart, D.S. “PolySearch: a web-based text mining system for extracting relationships between human diseases, genes, mutations, drugs and metabolites” Nucleic Acids Res. (2008). 36(Web Server issue):W399-405. Epub 2008 May 16.
• Forsythe, IJ, Wishart, DS. Exploring human metabolites using the human metabolome database. Curr Protoc Bioinformatics. 2009 Mar;Chapter 14:Unit14.8.
•  Frolkis, A., Knox, C., Lim, E., Jewison, T., Law, V., Hau, D., Liu, P., Gautam, B, Ly, S., Guo, A.C., Xia, J., Liang, Y., Shrivastava, S., Wishart, D.S. (2009)  "SMPDB: The Small Molecule Pathway Database"  (2010). Nucleic Acids Res 38(Database Issue) D480-7. EPub 2009 Nov 30.
• Knox, C., Shrivastava, S., Stothard, P., Eisner, R., Wishart, D.S. (2007). “BioSpider: a web server for automating metabolome annotations” Pacific Symposium on Biocomputing 12:145-56.
• Materi, W. and Wishart, D.S. “Computational Systems Biology in Drug Discovery and Development: Methods and Applications” Drug Discov Today. (2007). 12(7-8):295-303. Epub 2007 Mar 7.
• Poulin, B., Eisner, R., Szafron, D., Lu, P., Greiner, R., Wishart, D.S., Fyshe, A., Pearcy, B., MacDonell, C., Anvik, J. “Visual Explanation of Evidence in Additive Classifiers”. Proceedings of the 18th Conference on Innovative Applications of Artificial Intelligence (IAAI-06), pp. 1822-1829. Boston, MA, July 16-20, 2006.
• Wishart, D.S. Applications of metabolomics in drug discovery and development. Drugs in R&D. (2008). 9(5):307-22.
• Wishart, D.S. Current progress in computational metabolomics. Brief Bioinform. (2007). Sep;8(5):279-93. Epub 2007 Jul 11. 
• Wishart, D.S. Discovering drug targets through the web. Comparative Biochemistry and Physiology D-Genomics and Proteomics (2007). 2(1): 9-17.
• Wishart DS. DrugBank and its relevance to pharmacogenomics. Pharmacogenomics. (2008). 9(8):1155-62.
• Wishart, D.S. Human Metabolome Database: completing the 'human parts list' Pharmacogenomics. (2007). 8(7):683-6.
• Wishart DS. Identifying putative drug targets and potential drug leads: starting points for virtual screening and docking. Methods Mol Biol. (2008) 443:333-51.
• Wishart, D.S. Improving early drug discovery through ADME modelling: an overview. Drugs in R&D. 2007;8(6):349-62. 
• Wishart, D.S. Metabolomics: a complementary tool in renal transplantation. Contrib Nephrol. (2008) 160:76-87.
• Wishart, D.S. Metabolomics in Monitoring Kidney Transplants. Curr Opin Nephrol Hyperten (2006) 15(6):637-642 .
• Wishart, D.S. Proteomics and the human metabolome project. (Editorial) Expert Rev Proteomics. (2007) 4(3):333-5.
• Wishart,D.S. Quantitative metabolomics using NMR. Trends Analyt. Chem. (2008) 27(3): 228-237
• Wishart, D.S. and Greiner, R. “Computational Approaches to Metabolomics: An Introduction.” Pacific Symposium on Biocomputing 12:112-14 (2007).
• Wishart, D.S., Knox, C., Guo, A.C., Cheng, D., Shrivastava, S., Tzur, D., Gautam, B., Hassanali, M. DrugBank: a knowledgebase for drugs, drug actions and drug targets. Nucleic Acids Res. (2008) 36(Suppl 1):D901-6. Epub 2007 Nov 29. 
• Wishart, D.S., Knox, C., Guo, A.C., Eisner, R., Young, N., Gautam, B., Hau, D.D., Psychogios, N., Dong, E., Bouatra, S., Mandal, R., Sinelnikov, I., Xia, J., Jia, L., Cruz, J.A., Lim, E., Sobsey, C.A., Shrivastava, S., Huang, P., Liu, P., Fang, L., Peng, J., Fradette, R., Cheng, D., Tzur, D., Clements, M., Lewis, A., De Souza, A., Zuniga, A., Dawe, M., Xiong, Y., Clive, D., Greiner, R., Nazyrova, A., Shaykhutdinov, R., Li, L., Vogel, H.J., Forsythe, I. HMDB: a knowledgebase for the human metabolome. Nucleic Acids Res. (2009) 37(Suppl 1):D603-10. Epub 2008 Oct 25.
• Wishart, D.S., Lewis, M.J., Morrissey, J.A., Flegel, M.D., Jeroncic, K., Xiong, Y., Cheng, D., Eisner, R., Gautam, B., Tzur, D., Sawhney, S., Bamforth, F., Greiner, R., Li, L. “The human cerebrospinal fluid metabolome” J Chromatogr B Analyt Technol Biomed Life Sci. (2008)871(2):164-173. Epub 2008 May 8.
• Wishart, D.S., Tzur, D., Knox, C., Eisner, R., Guo, A.C., Young, N., Cheng, D., Jewell, K., Arndt, D., Sawhney, S., Fung, C., Nikolai, L., Lewis, M., Coutouly, M.A., Forsythe, I., Tang, P., Shrivastava, S., Jeroncic, K., Stothard, P., Amegbey, G., Block D., Hau, D.D., Wagner, J., Miniaci, J., Clements, M., Gebremedhin, M., Guo, N., Zhang, Y., Duggan, G.E., Macinnis, G.D., Weljie, A.M., Dowlatabadi, R., Bamforth, F., Clive, D., Greiner, R., Li, L., Marrie, T., Sykes, B.D., Vogel, H.J., Querengesser, L. “HMDB: the Human Metabolome Database.” Nucleic Acids Res. (2007) 35(Suppl 1):D521-526.
• Xia, J., Bjorndahl, T.C., Tang, P., Wishart, D.S. MetaboMiner--semi-automated identification of metabolites from 2D NMR spectra of complex biofluids. BMC Bioinformatics. (2008) 9:507-522.
• Xia,J., Psychogios, N., Young, N., Wishart, D.S. (2009) MetaboAnalyst: a web server for metabolomic data analysis and interpretation.  Nucleic Acids Res 37(Web Server Issue):W652-660.  e-Published May 8 2009
• Zhang, N., Chen, R., Young, N., Wishart, D., Winter, P., Weiner, J.H., Li, L. Comparison of SDS- and methanol-assisted protein solubilization and digestion methods for Escherichia coli membrane proteome analysis by 2-D LC-MS/MS. Proteomics. (2007) 7(4):484-93

Book Chapters / Contributions to a Collective Work

• Wishart, D.S. "Bioinformatics for Metabolomics.” In S. Krawetz (ed)  Computational Systems Biology. Humana Press, Totowa NJ pp. 581-680 (2009).
• Wishart, D.S. “In Silico Drug Exploration and Discovery using DrugBank.” In A. Baxevanis (ed) Current Protocols in Bioinformatics.  Current Protocols, Wiley Interscience, NY, Chapter 14.4 (2007).
• Wishart, D.S. “Introduction to Cheminformatics." In A. Baxevanis (ed) Current Protocols in Bioinformatics. Current Protocols, Wiley Interscience, NY, Chapter 14.1 (2007).
• Wishart, D.S. “Drug-Target Discovery In Silico: Using the Web to Identify Novel Molecular Targets for Drug Action.” In Parrington, J., Coward, K. (eds) Comparative Genomics and Proteomics in Drug Discovery. Taylor and Francis, Abingdon, UK pp. 145-176 (2006).
• Wishart, D.S. "Metabolomics in Humans and Other Mammals" In Villas-Boas, S.G., Nielsen, J, Smedsgaard, J., Hansen, M.A.E., Roessner-Tunali, U. (eds) Metabolome Analysis: An Introduction. John Wiley & Sons, New York pp. 280-296 (2007).
• Wishart, D.S. “Metabolism and Metabolic Disease Resources on the Web.” In Scriver Baudet, Sly, Valle, Childs, Kinzler, Vogelstein (eds) On-line Molecular and Metabolic Basis of Inherited Disease – OMMBID. John Wiley & Sons, New York, Chapter 3.1 (2006).
• Wishart, D.S. “Metabolomics for Drug Discovery, Development and Monitoring” Touch Briefings – Future Drug Discovery pp. 1-3 (2006).

Presentations

• Ametaj BN, Emmanuel DGV, Lewis MJ, Jeroncic K, Nikolai L, Shanthipoosan S, Wishart DS. "Bovine Metabolomics: Profiling of Rumen Fluid Metabolites in Dairy Cattle", poster presented at the Second Annual Metabolomics Symposium: Exploring the Human Metabolome poster session, Timms Centre at the University of Alberta on October 12, 2006.
• Wishart, D.S. “A New Strategy for Disease Diagnosis” presented at the U of A Alumni Association Meeting in Edmonton, AB - April 20, 2006.
• Wishart, D.S. “Applications of Metabolomics in Nutritional Science” presented at the University of North Carolina (Chapel Hill), Chapel Hill, NC, Feb. 13, 2008.
• Wishart, D.S.  “Bioinformatics and the Human Metabolome Project” presented at the first annual Who We Are and What We Eat Conference, Charlotte NC, April 17, 2007. 
• Wishart, D.S. “Computational Approaches to Metabolomics: A Tutorial” presented at the 2007 Pacific Symposium on Biocomputing, Maui, Hawaii, Jan 4. 2007.
• Wishart, D.S. “DrugBank2” presented at the EBI Druggability Portal Workshop, Cambridge, England, Feb. 4, 2008.
• Wishart, D.S. “How Bioinformatics Helped Reveal the Human Metabolome” presented at InCOB 2007, Hong Kong, Aug. 28, 2007.
• Wishart DS. “Informatics and Metabolomics” Presented at the Elixir/EBI Metabolomics Workshop, Hinxton, UK, Jan. 27, 2009
• Wishart, D.S. “Introduction to Computational Aspects of Metabolomics” presented at the 2007 Pacific Symposium on Biocomputing, Maui, Hawaii, Jan 4. 2007.
• Wishart, D.S. “Metabolomics in Canada” presented at the Genome Canada Proteomics Workshop in Montreal July 12, 2006.
• Wishart DS. “Metabolomics for monitoring and optimizing microbial xylose fermentation”, Presented at the First Annual General Meeting of the CBioN (Cellulosic Biofuels Network), Montreal, March 27, 2009
• Wishart, D.S. “Metabolomics: The Capstone to Systems Biology” presented at the Omics & Systems Biology CPS-Regional Meeting, Edmonton, AB, Feb. 21, 2008.
• Wishart, D.S. “Metabolomics: The Next Frontier for Bioinformatics?” presented at the Rocky 06 Conference in Snowmass CO December 2, 2006.
• Wishart, D.S. “Metabolomics: The Other Side of Proteomics” presented at the APIII 2006 (Advancing Practice through Instruction, Innovation and Informatics) Conference in Vancouver August 17, 2006.
• Wishart, D.S. “Nutrigenomics Research in Alberta” presented at the Canadian Nutrigenomics Workshop in Montreal, Quebec October 3, 2006.
• Wishart DS. “The Human Biofluid Metabolomes: Different Answers from Different Technologies”, Presented at the NuGO & SysDiet Metabolomics Workshop, Copenhagen DK, Feb. 23, 2009
• Wishart, D.S. “The Human Metabolome Project: An Update” presented at the 2nd Annual Conference on Understanding the Human Metabolome in Edmonton, AB October 12, 2006.
• Wishart, D.S. “The Human Metabolome Project” presented at the 5th Northern Lights Summer Conference on Metabolomics: Technologies & Applications, Waterloo ON, June 21, 2007. 
• Wishart, D.S. “The Metabolomics ToolBox: Applications to Organ Transplant Monitoring” presented at the ATAGC Conference – Using Omics Technologies to Phenotype Diseases, Edmonton AB, June 18, 2007
• Xia, J. (2009).  "Metabolomic Data Processing & Statistical Analysis".  5th International Conference of the Metabolomics Society Aug 30 - Sept 2
  

Posters

• Cheng, D., Zhang, H., Young, N., Knox, C., Stothard, P., Damaraju, S., Wishart, D.S. "PolySearch: A Web Based Text Mining System for Extracting Relationships between Diseases, Genes, Mutations, Drugs and Metabolites", poster presented at the Alberta Cancer Board's Annual Research Meeting, Banff, AB. Nov. 7-9, 2006.  
• Eisner, R., Greiner, R., Wishart, D.S. “Chemical Class Prediction in the Human Metabolome”, poster presented at the Canadian Proteome Society Regional Meeting – Omics & Systems Biology, Edmonton, AB, Feb. 21-22, 2008.
• Eisner, R., Knox, C., Cheng, D., Greiner, R., Wishart, D.S. “Text Analysis in the Human Metabolome Project”, poster presented at the 3rd Annual Meeting of the Metabolomics Society, Manchester UK, June 11-14, 2007.
• Eisner, R., Knox, C., Cheng, D., Greiner, R., Wishart, D.S. “Text Analysis in the Human Metabolome Project”, poster presented at the 5th Annual Northern Lights Summer Conference on Metabolomics, Technologies & Applications, Waterloo ON, June 20-22, 2007.
• Forsythe, I., Wishart, D.S., Li, L., Greiner, R., Sykes, B.D., Bamforth, F., Clive, D., Vogel, H. “Metabolomics – Revolutionizing Healthcare, Agriculture, Nutrition and Food Production in the 21st Century”, poster presented at the Canadian Proteome Society Regional Meeting – Omics & Systems Biology, Edmonton, AB, Feb. 21-22, 2008.
• Frolkis, A., Knox, C., Lim, E., Jewison, T., Law, V., Hau, D., Liu, P., Gautam, B, Ly, S., Guo, A.C., Xia, J., Liang, Y., Shrivastava, S., Wishart, D.S. (2009)  "SMPDB: The Small Molecule Pathway Database"  5th International Conference of the Metabolomics Society (Aug 30 - Sept 2). 
• Hau, D.D., Xia, J., Wishart, D.S. "In Vitro Metabolic Mapping by NMR Spectroscopy: Part 1 of the Four-Dimensional Project", poster presented at the Second Annual Metabolomics Symposium: Exploring the Human Metabolome poster session at the Timms Centre, University of Alberta on October 12, 2006.
• Jia, L., Wishart, D.S. “NMR-Star Converter and Chemical Shift Editor”, poster presented at the Canadian Proteome Society Regional Meeting – Omics & Systems Biology, Edmonton, AB, Feb. 21-22, 2008.
• Lewis, M.J., Morrissey, J., Jeroncic, K.G., Wishart, D.S.. “Identification and Quantification of the Human CSF Metabolome”, poster presented at the 5th Annual Northern Lights Summer Conference on Metabolomics, Technologies & Applications, Waterloo ON, June 20-22, 2007.
• Lewis, M.J., Nikolai, L.N., Jeroncic, K.G., Wishart, D.S. "Identification and Quantification of the Human CSF Metabolome", poster presented at the Second Annual Metabolomics Symposium: Exploring the Human Metabolome poster session at the Timms Centre, University of Alberta  October 12, 2006.
• Peng, J., Hau, D.D., Xia, J., Lewis, M.J., Wishart, D.S. “Human Serum Metabolomics Studied by 1H NMR”, poster presented at the 5th Annual Northern Lights Summer Conference on Metabolomics, Technologies & Applications, Waterloo ON, June 20-22, 2007.
• Peng, J., Psychogios, N., Wishart, D.S. “Human Blood Serum Metabolomics Studied by GC-MS”, poster presented at the Canadian Proteome Society Regional Meeting – Omics & Systems Biology, Edmonton, AB, Feb. 21-22, 2008.
• Tang, P., Arndt, D., Cruz, J., Yang, R., Fung, C., Wishart, D.S. “Dynamic Cellular Automata: An Alternative Approach to Cellular Simulation”, poster presented at the CPI 2007 Meeting, Ottawa ON, June 16-18, 2007.
• Wagner, J., Greiner, R., Baracos, V., Mourtzakis, M., Prado, C., Slupsky, C., Rankin, K., Chang, D., McGeer, A., Marrie, T., Nikolai, L., Lewis, M,. Coutouly, M-A., Wishart, D.S. "Using Metabolomic Profiles to Diagnose Patients", poster presented at the Second Annual Metabolomics Symposium: Exploring the Human Metabolome poster session at the Timms Centre, University of Alberta October 12, 2006
• Xia, J., Lewis, M.J., Wishart, D.S. “Automatics Metabolite Identification in Biofluids Using 2D TOCSY Spectroscopy”, poster presented at the 5th Annual Northern Lights Summer Conference on Metabolomics, Technologies & Applications, Waterloo ON, June 20-22, 2007.
• Xia, J., Psychogios, N., Young, N., Wishart, D.S. (2009) "MetaboAnalyst - A web service for metabolic data processing and analysis"  5th International Conference of the Metabolomics Society Aug 30 - Sept 2. 
• Young, N., Jewell, K., Block, D., Knox, C., Tang, P., Greiner, R., Wishart, D.S. "MetaboLIMS: A General Laboratory Information Management System for Metabolomics", poster presented at the Second Annual Metabolomics Symposium: Exploring the Human Metabolome poster session at the Timms Centre, University of Alberta October 12, 2006