4D Project Overview

Building on the highly successful integrated and distributed Bioinformatics Platform for Genome Canada, Dr. Sensen’s team has become one of a few in the world with the computational power to successfully undertake this type of 4D initiative using spatial and temporal data.

The 4D Project provides services based on the 4D visualization system currently in place at the Sun Center of Excellence for Visual Genomics (COE). Research groups worldwide can access this powerful new technology, significantly impacting Canadian and international genetic disease research with the potential to deliver wide-ranging socio-economic advances.

The Project is organized into five components, four of which are separate biomedical case studies with their own research objectives.These four components serve as sources of experimental data and user expertise. The fifth component, led by Dr. Sensen's team at the University of Calgary, combines the knowledge gained from these four components into a unified 4D system for data analysis and visualization, making the system capable of handling these four very diverse case studies, as well as generic and extendible to new research scenarios.

• Development of the Core Visualization Infrastructure Through Genetic Disease Data 4D Visualization
• Developmental Genetics of Craniofacial Shape in Mice
• Genomic Markers of Multiple Sclerosis and Responsiveness to Drug Therapy in Humans
  
• Polygenetic Causes of Obesity in Mice
• Metabolomics in Humans, Mice, and Rats